Protein Resins
Genscript Corporation AmMag Ultra AT protein A mag
AmMag Ultra AT Protein A Magbeads are developed and optimized for antibody purification for high throughput and high volume applications and can withstand 1M alkali
Genscript Corporation Protein G Resin FF
GenScript Protein G Resin FF is an affinity chromatography medium designed for easy one-step purification of classes subclasses and fragments of immunoglobulins from biological fluids and from cell culture media
Genscript Corporation iFluor647-Protein L
Protein L is a cell surface protein from Peptostreptoccocus magnus that binds to the variable light chains (kappa chain) of immunoglobulins without interfering with antigen binding In contrast to IgG-binding proteins such as protein A and protein G which bind to the Fc region of immunoglobulins protein L can be used for the detection and purification of mammalian kappa light chain antibodies of all classes Since no part of the heavy chain is involved in the binding interaction Protein L binds a wider range of antibody classes than Protein A or G Protein L binds to representatives of all antibody classes including IgG IgM IgA IgE and IgD Single chain variable fragments (scFv) and Fab fragments also bind to Protein L
Genscript Corporation Streptavidin MagBeads
GenScript Streptavidin MagBeads are ideal for fast and convenient purification of biotinylated proteins peptides antibodies and oligonucleotides and protein interaction studies
Genscript Corporation Monofinity A Resin
GenScript s Monofinity A Resin is made of recombinant protein A as ligand which not only keeps the specific binding capacity to Fc region of immunoglobulin molecules but also enhances chemical stability under Cleaning-in-place (CIP) conditions
Genscript Corporation Protein A/G Magbeads MX
The GenScript Protein A/G MagBeads MX are ideal for small scale purification of antibodies from plasma serum ascites and cell culture
Essendant Universal White Labels Inkjet/Laser Printers 0 5x1 75 White 80/Sheet 100 Sheets/Box
Universal White Labels Inkjet/Laser Printers 0 5x1 75 White 80/Sheet 100 Sheets/Box
AdipoGen NAPRTase B Subtilis rec
Protein. Full-length NAPRTase Bacillus subtilis. Source E. coli. Endotoxin content N/A. Liquid. in 20mM TRIS-HCl, pH 7.8 containing 50mM sodium chloride. Purity >98% SDS-PAGE. Nicotinate Phosphoribosyltransferase NAPRTase is involved in the biological processes of pyridine nucleotide biosynthesis and nicotinate nucleotide salvage and functions by catalyzing the conversion of nicotinic acid NA to NA mononucleotide NaMN. It is a crucial factor in the NAD biosynthesis pathway. Catalytic activity Beta-nicotinate D-ribonucleotide diphosphate = nicotinate 5-phospho-alpha-D-ribose 1-diphosphate.
AdipoGen Flagellin rec untagged
Recombinant protein. Native flagellin FliC from Salmonella enterica Serovar Typhimurium strain ATCC14028 aa 1-495. Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 CXCL8, CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin MMP-7. Maturation of dendritic cells in in vitro and in vivo assays. Adjuvant activity on foreign antigens delivered by subcutaneous and intranasal routes in mice. TLR5 can be stimulated in vitro by Flagellin rec. untagged highly active at a concentration of 5-50ng/ml and in vivo at a starting concentration of 0.1-1µg/mouse. Source E. coli. Lyophilized. Contains PBS. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 TLR5 and the intracellular protein NLRC4 NLR family CARD domain-containing protein 4.
AdipoGen EGFR Soluble human rec
Protein. Human EGFR 629aa is fused at the C-terminus to a Strep-tag. Source Sf9 cells. Lyophilized. Purity >90% SDS-PAGE. EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
AdipoGen izTRAIL Soluble h rec
Protein. The extracellular domain of human TRAIL aa 95-281 is fused at the N-terminus to an isoleucine zipper motif. Source E. coli. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains 20mM TRIS-Cl, 0.5M arginine-HCl, 100mM NaCl, 0.02% Tween 20. Binds to human TRAIL receptors 1-4 TRAIL-R1 to TRAIL-R4 izTRAIL does not interact with the apoptosis-inducing mouse TRAIL receptor TRAIL-R. Purity >95% SDS-PAGE. izTRAIL is a newly available, highly active recombinant form of soluble human TRAIL. Due to a trimerizing N-terminal isoleucine zipper iz motif the intrinsic trimerization of TRAIL, required for apoptosis-inducing activity of TRAIL, is enhanced when compared to non-tagged soluble human TRAIL shTRAIL. Therefore, izTRAIL is a potent inducer of apoptosis in many human cancer cells, but not normal human hepatocytes. In addition, the half-life of izTRAIL is about eight-fold higher than the half-life of shTRAIL.
AdipoGen DLL1 human rec
Protein. Signal peptide and extracellular domain of human DLL1 aa 1-545 are fused at the C-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS. Purity >90% SDS-PAGE. The Notch ligand delta-like protein 1 DLL1 is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
AdipoGen Fc humanFGL1 human rec
Recombinant Protein. Human FGL1 aa 23-312 is fused at the N-terminus to the Fc portion of human IgG1 and at the C-terminus to a His-Tag. Should activate human LAG-3 activity test not yet performed. Source/Host HEK 293 cells. Endotoxin <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. FGL1 Fibrinogen-like protein 1 also called Hepatocyte-derived fibrinogen-related protein 1 HFREP-1 or Hepassocin was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript enriched in regenerating liver. FGL1 is expressed at lower levels in brown and white adipose in the setting of liver injury. A low level expression of FGL1 is also observed in the pancreas. FGL1 is a 34 kDa protein structurally similar to Angiopoietin-like factors 2, 3, 4 and 6, which regulate lipid metabolism and energy utilization.
AdipoGen Progranulin human rec
Protein. Signal peptide and human progranulin aa 1-593 are fused at the C-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >98% SDS-PAGE. Progranulin PGRN is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration FTLD. In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease AD and potentially for MCI Mild Cognitive Impairment. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.